Hodgdon Pyrodex RS can be used in all calibers of percussion muzzleloading rifles and shotguns. It has a wide application of uses and is the most versatile powder in the Pyrodex line. Like all grades of Pyrodex, it burns cleaner and produces less fouling than blackpowder. RS compares to 2F blackpowder on a particle size basis. Note:Do not exceed the loads displayed in the reloaders guide. Never mix any two powders regardless of type, brand, or source. Never substitute any smokeless powder for Black Powder or any Black Powder substitute.