The Women's Brooks Glycerin 22 Running Shoe is designed for runners seeking supreme comfort. This supportive road running shoe features DNA Tuned cushioning to keep the landings plush and toe-offs responsive. GuideRail technology offers support through your natural stride, so you stay on track throughout the run. Built with an engineered double jacquard knit upper, there is plenty of breathability and flexibility to keep you going through hot weather and long, sweaty runs.